The effects of dehydration on the body are often underestimated, though water makes up nearly 60% of human composition and is vital for survival.
Water is the cornerstone of human survival. Nearly 60–70% of the adult body is made up of water, and it is indispensable for almost every physiological process, from cellular metabolism to temperature regulation. Despite this, dehydration—the state in which the body loses more water than it takes in and a water deficiency happens in the body—is a widespread but underestimated health risk. It is not merely a condition of “feeling thirsty.” Dehydration can impair organ function, contribute to the progression of serious diseases, and in severe cases, threaten life itself.
In this article, we explore the scientific basis of dehydration, its effects on different organs, the diseases it may trigger, diagnostic methods, and how individuals can safeguard themselves.
Table of Contents
What Happens in the Body During Dehydration?
At a biochemical level, dehydration leads to an imbalance in water and electrolytes such as sodium, potassium, and chloride. Since water is vital for transporting nutrients, removing waste, and maintaining blood pressure, even a small reduction can cause widespread physiological stress.

Studies show that losing just 1–2% of body water can impair cognitive performance, mood, and alertness (Armstrong et al., 2012). When dehydration becomes moderate (5–8% fluid loss), symptoms like dizziness, confusion, and fatigue appear. Severe dehydration (>10%) can even lead to organ failure and death.
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Symptoms of Dehydration
Dehydration symptoms may vary depending on the severity and the individual’s age.
Early Signs:
- Dry mouth, cracked lips, and decreased saliva
- Dark yellow urine or reduced urination
- Fatigue, dizziness, and headaches
- Difficulty concentrating or mild irritability
Severe Signs:
- Rapid heartbeat and low or high blood pressure
- Sunken eyes, dry skin with poor elasticity
- Delirium, confusion, or fainting
- In infants: lack of tears, dry tongue, and unusually long sleep
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Diseases Linked to Dehydration
Chronic or recurrent dehydration is not merely uncomfortable—it can pave the way for serious diseases.
- Kidney Disorders
- Concentrated urine increases the risk of kidney stones and urinary tract infections (UTIs).
- Long-term water deficiency contributes to chronic kidney disease (CKD).
- Digestive Problems
- Lack of water leads to constipation and poor nutrient absorption.
- Dehydration can also worsen acid reflux due to reduced saliva production.
- Neurological Issues
- Dehydration shrinks brain cells temporarily, leading to confusion, poor memory, and attention deficits.
- Severe cases can mimic symptoms of dementia in elderly patients.
- Cardiovascular Strain
- Reduced blood plasma volume makes blood thicker, forcing the heart to work harder.
- This increases risks of hypertension, arrhythmias, and stroke.
- Heat-Related Illnesses
- In hot climates, dehydration accelerates heat exhaustion and can cause heatstroke, a potentially fatal condition.
- Skin and Joint Problems
- Dry skin, reduced elasticity, and poor wound healing are common.
- Cartilage lubrication diminishes, worsening joint stiffness and arthritis pain.
A 2010 review in Nutrition Reviews confirmed that inadequate hydration plays a direct role in conditions like constipation, kidney stones, and impaired cognition (Popkin et al., 2010).
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Diagnostic Tests for Dehydration and Related Conditions
Doctors use several tests to evaluate dehydration and its complications:
- Urinalysis: Measures urine concentration, pH, and signs of infection.
- Serum Electrolyte Tests: Detect sodium, potassium, and chloride imbalance.
- Plasma Osmolality: Assesses the body’s hydration status at a cellular level.
- Kidney Function Tests: Blood urea nitrogen (BUN) and creatinine levels determine kidney health.
- Imaging (Ultrasound/CT scans): Useful in diagnosing kidney stones or urinary blockages.
- Cognitive Assessment: Particularly in elderly patients, to check dehydration-induced mental decline.
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Treatment of Dehydration
Mild to Moderate Dehydration
- Drinking water slowly in small sips.
- Consuming oral rehydration solutions (ORS) that contain sodium, potassium, and glucose for better absorption.
- Eating water-rich foods like cucumbers, oranges, watermelon, etc.
Severe Dehydration
- Intravenous (IV) fluids in hospital settings.
- Electrolyte correction under medical supervision.
- Monitoring of heart, kidney, and liver function.
Infants and elderly individuals are particularly vulnerable and require immediate medical attention when severe symptoms appear.
How Much Water Should You Drink?
The National Academies of Sciences (U.S.) recommends the following daily fluid intake, which includes water, other beverages, and food moisture:
- Adult men: ~3.7 liters/day
- Adult women: ~2.7 liters/day
- Children (9–13 years): 2.1–2.4 liters/day
- Teenagers: 2.3–3.3 liters/day
However, climate and activity levels change these needs. For example:
- Hot climates: Increase intake by 0.5–1 liter/day.
- Athletes: Require extra fluids and electrolyte replacement.
- Cold climates: Hydration must still be maintained despite low thirst perception.
Awareness and Prevention
Dehydration is preventable with consistent awareness and lifestyle choices. Here are scientifically supported strategies:
- Start the day with a glass of water.
- Use hydration reminders or apps.
- Choose water over caffeinated or alcoholic beverages, as the latter act as diuretics.
- Encourage children and the elderly to drink even if they don’t feel thirsty.
- During illnesses with fever, diarrhea, or vomiting, increase fluid intake and consider ORS.
- Public health campaigns should emphasize hydration in schools, workplaces, and communities, especially in regions with hot weather.
The World Health Organization (WHO) also emphasizes the importance of safe drinking water access as a global preventive measure against dehydration and waterborne illnesses (WHO, 2022).
Conclusion
Dehydration is not simply about thirst—it is a systemic health threat that can impair cognition, damage kidneys, increase cardiovascular risks, and reduce overall well-being. Early recognition of symptoms and timely interventions are crucial. With proper hydration habits, adequate testing, and awareness, the severe complications of dehydration can be avoided.
In an era where lifestyle diseases are on the rise, water is one of the simplest, most cost-effective medicines available. Staying hydrated is more than a wellness trend; it is a lifesaving necessity.
References
- Armstrong, L. E., Ganio, M. S., Casa, D. J., et al. (2012). Mild dehydration affects mood in healthy young women. Journal of Nutrition, 142(2), 382–388. https://doi.org/10.3945/jn.111.142000
- Popkin, B. M., D’Anci, K. E., & Rosenberg, I. H. (2010). Water, hydration, and health. Nutrition Reviews, 68(8), 439–458. https://doi.org/10.1111/j.1753-4887.2010.00304.x
- Institute of Medicine. (2005). Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. National Academies Press.
- World Health Organization. (2022). Drinking-water: Key Facts. Retrieved from https://www.who.int/news-room/fact-sheets/detail/drinking-water
- The Independent. (2024). Dehydration symptoms: Why water and electrolytes matter.